San Diego's commercial real estate market is experiencing a notable shift in office leasing dynamics, with current vacancy rates hovering around 13 percent, driven primarily by a hybrid work model. While larger companies are downsizing their footprints, the demand for flexible workspace solutions is on the rise, particularly in the coworking segment, which continues to thrive as small businesses seek adaptable options. Coworking spaces now make up a significant share of the market, catering to startups and freelancers who prioritize flexibility and community.
Health indicators, such as rising rental rates in prime areas, signal a competitive landscape for quality spaces, but small businesses should strategize on leases that offer short term commitments and growth potential. Key insights for these businesses include focusing on neighborhoods with strong amenities and transportation access, as these aspects enhance employee satisfaction and retention. Overall, navigating the current market requires a keen understanding of emerging trends and tailored approaches to leasing.
Rofo researches and displays commercial real estate listings from top brokerage firms and landlords in San Diego, CA making it easier to find available commercial space and compare current asking rental rates. In San Diego, CA there are currently 1,454 office spaces for lease, 289 warehouse spaces for rent, 223 retail spaces, and 230 shared office spaces (also known as co-working spaces and executive suites) with 167 real estate professionals to help you find the right space for you. Sizes range from 200 square feet up to 10,997,805 square feet. Filter your search below and get free advice from recommended brokers in San Diego, CA.
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Showing 21 - 40 of 872 buildings with 2,041 total listings
3570 Carmel Mountain Rd, San Diego, CA 92130
3570 Carmel Mountain Rd is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by Cassidy Turley BRE.
Easy access to I-5 and State Route 56 Lots of natural light Move-in ready
2 office spaces from 3,420 to 48,041 square feet.
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9530 Padgett St, San Diego, CA 92126
9530 Padgett St is a mixed-use property for lease in San Diego, CA. The property currently has 2 industrial spaces and 1 office space for lease and is marketed by Cassidy Turley BRE.
2 industrial spaces and 1 office space from 3,861 to 15,498 square feet.
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9520 Padgett St, San Diego, CA 92126
9520 Padgett St is a mixed-use property for lease in San Diego, CA. The property currently has 2 office spaces and 5 retail spaces for lease and is marketed by Cassidy Turley BRE and Voit Commercial.
High image multi-tenant business park Recently renovated interior and exterior Centally located and minutes from freeways
2 office spaces and 
5 retail spaces from 743 to 5,744 square feet.
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2225 Avenida Costa Este, San Diego, CA 92154
2225 Avenida Costa Este is a mixed-use property for lease in San Diego, CA. The property currently has 5 industrial spaces and 1 office space for lease and is marketed by Cassidy Turley BRE.
5 industrial spaces and 1 office space from 3,531 to 33,786 square feet.
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3661 Valley Centre Dr, San Diego, CA 92130
3661 Valley Centre Dr is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBRE San Diego.
Project Totals Approximately 536,000 Square Feet On-site Fitness Center with Shower and Locker Facilities Unparalleled Freeway Visibility EV...
1 office space 9,683 square feet.
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12625 High Bluff Dr, San Diego, CA 92130
12625 High Bluff Dr is an office property for lease in San Diego, CA. The property currently has 3 office spaces for lease and is marketed by CBRE San Diego.
Unique Spanish Colonial architecture in Del Mar Heights, open-air courtyard with lush garden and outdoor cafˇ, state-of-the-art common area conference...
3 office spaces from 1,212 to 1,408 square feet.
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8880 Rio San Diego Dr, San Diego, CA 92108
8880 Rio San Diego Dr is an office property for lease in San Diego, CA. The property currently has 14 office spaces for lease and is marketed by CBRE San Diego.
The premier Class A office tower in the heart of Mission Valley | Convenient location with instant access to major highways; 10 minutes from...
14 office spaces from 120 to 12,477 square feet.
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16870 W Bernardo Dr, San Diego, CA 92127
16870 W Bernardo Dr is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Search Office Space.
Located just west of I-15 in Rancho Bernardo convienent to the freeway.
1 office space 150 square feet.
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11440 W Bernardo Ct, San Diego, CA 92127
11440 W Bernardo Ct is an office property for lease in San Diego, CA. The property currently has 5 office spaces for lease and is marketed by CBRE San Diego and Search Office Space.
Located in the heart of Ranch Bernardo business district. Freeway visibility and easy access to I-15 at Rancho Bernardo Rd. Proximity to retail...
5 office spaces from 120 to 1,834 square feet.
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12230 El Camino Real, San Diego, CA 92130
12230 El Camino Real is an office property for lease in San Diego, CA. The property currently has 4 office spaces for lease and is marketed by Cassidy Turley BRE.
4 office spaces from 2,657 to 26,799 square feet.
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5005 Texas St, San Diego, CA 92116
5005 Texas St is an office property for lease in San Diego, CA. The property currently has 3 office spaces for lease and is marketed by .
3 office spaces from 2,835 to 7,151 square feet.
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4141 Jutland Dr, San Diego, CA 92117
4141 Jutland Dr is an office property for lease in San Diego, CA. The property currently has 4 office spaces for lease and is marketed by McKee Commercial.
Building signage opportunities Common area men's and women's restrooms on each floor
4 office spaces from 696 to 15,493 square feet.
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6390 Greenwich Dr, San Diego, CA 92122
6390 Greenwich Dr is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by .
Located on the corner of Greenwich Drive and Governor Drive. Quick access to Interstate 805.
2 office spaces from 1,584 to 2,531 square feet.
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6150 Mission Gorge Rd, San Diego, CA 92120
6150 Mission Gorge Rd is an office property for lease in San Diego, CA. The property currently has 11 office spaces for lease and is marketed by .
Central San Diego location. Right off of Interstate 8.
11 office spaces from 1,586 to 7,665 square feet.
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2970 5th Ave, San Diego, CA 92103
2970 5th Ave is an office property for lease in San Diego, CA. The property currently has 4 office spaces for lease and is marketed by CBRE San Diego.
Located in Hillcrest. Walk to shops, restaurants, and Balboa Park.
4 office spaces from 2,393 to 5,485 square feet.
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2250 4th Ave, San Diego, CA 92101
2250 4th Ave is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by .
Located in San Diego's Bankers Hill it is walking distance to Balboa Park, near Downtown and Hillcrest.
2 office spaces from 2,103 to 2,769 square feet.
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3914 Murphy Canyon Rd, San Diego, CA 92123
3914 Murphy Canyon Rd is an office property for lease in San Diego, CA. The property currently has 3 office spaces for lease and is marketed by PS Business Parks.
This park encompasses over 164,000 square feet of distinctive office and flex space. Tree lined walkways surround the two story buildings on...
3 office spaces from 434 to 2,503 square feet.
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