Office spaces in San Diego are seeing increasing demand from technology and life sciences firms, particularly in hubs like UTC, Sorrento Valley, and Downtown. The industrial market remains strong due to e-commerce growth and the region's strategic logistics advantages. Retail spaces are rebounding, with a focus on experiential and mixed-use developments catering to the city's vibrant population and tourism industry.
San Diego's business-friendly climate, highly educated workforce, and strong research institutions, including UC San Diego, attract companies seeking innovation and collaboration. Additionally, the city's quality of life—boasting year-round mild weather, cultural amenities, and outdoor activities—further draws talent and businesses to the area.
Rofo researches and displays commercial real estate listings from top brokerage firms and landlords in San Diego, CA making it easier to find available commercial space and compare current asking rental rates. In San Diego, CA there are currently 1,454 office spaces for lease, 289 warehouse spaces for rent, 223 retail spaces, and 230 shared office spaces (also known as co-working spaces and executive suites) with 167 real estate professionals to help you find the right space for you. Sizes range from 200 square feet up to 10,997,805 square feet. Filter your search below and get free advice from recommended brokers in San Diego, CA.
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Showing 121 - 140 of 871 buildings with 2,040 total listings
1111 6th Ave, San Diego, CA 92101
1111 6th Ave is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by CBRE San Diego and Perry Commercial RE.
On site storage Game room with ping pong and pool table 24/7 access to the building Unlimited coffee and beer Mail and parcel service Fiber optic...
2 office spaces from 1,660 to 10,002 square feet.
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9245 Activity Rd, San Diego, CA 92126
9245 Activity Rd is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Cassidy Turley BRE.
1 office space from 2,367 to 11,493 square feet.
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2851 Camino del Rio S, San Diego, CA 92108
2851 Camino del Rio S is an office property for lease in San Diego, CA. The property currently has 3 office spaces for lease and is marketed by Cassidy Turley BRE.
3 office spaces from 1,116 to 5,255 square feet.
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4850 Pacific Hwy, San Diego, CA 92110
4850 Pacific Hwy is a mixed-use property for lease in San Diego, CA. The property currently has 1 industrial space and 1 office space for lease and is marketed by .
1 industrial space and 1 office space from 3,588 to 18,335 square feet.
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11107 Roselle St, San Diego, CA 92121
11107 Roselle St is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Voit Commercial.
Industrial space for lease
1 office space 1,832 square feet.
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3666 Kearny Villa Rd, San Diego, CA 92123
3666 Kearny Villa Rd is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Cassidy Turley BRE.
1 office space from 6,764 to 9,764 square feet.
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350 Camino de la Reina, San Diego, CA 92108
350 Camino de la Reina is an office property for lease in San Diego, CA. The property currently has 5 office spaces for lease and is marketed by CBRE San Diego.
Mission Valley Landmark Office Building with efficient access to I-8 and I-163.
5 office spaces from 15,936 to 52,196 square feet.
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9635 Granite Ridge Dr, San Diego, CA 92123
9635 Granite Ridge Dr is an office property for lease in San Diego, CA. The property currently has 16 office spaces for lease and is marketed by CBRE San Diego.
Office space in San Diego
16 office spaces from 1,168 to 56,277 square feet.
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525 B St, San Diego, CA 92101
525 B St is an office property for lease in San Diego, CA. The property currently has 9 office spaces for lease and is marketed by CBRE San Diego.
Located in the heart of the Core Business District
Space is located on the ground floor of a 427,000 SF office tower
Building is situated...
9 office spaces from 2,828 to 19,823 square feet.
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101 W Broadway, San Diego, CA 92101
101 W Broadway is an office property for lease in San Diego, CA. The property currently has 3 office spaces for lease.
Beautiful business center, located in a Class A high rise building in the heart of Downtown San Diego. This 74 office business center is...
3 office spaces from 120 to 20,324 square feet.
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3456 Camino del Rio N, San Diego, CA 92108
3456 Camino del Rio N is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Voit Commercial.
Fully Furnished Suite with reception, conference room, storage room, and 4 private offices.
1 office space from 895 to 9,146 square feet.
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123 Camino de la Reina, San Diego, CA 92108
123 Camino de la Reina is an office property for lease in San Diego, CA. The property currently has 12 office spaces for lease and is marketed by and Cassidy Turley BRE.
Walking distance to Trolley and Fashion Valley mall. Easy access to Highway 163 & Interstate 8.
12 office spaces from 1,287 to 29,900 square feet.
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6362 Ferris Sq, San Diego, CA 92121
6362 Ferris Sq is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Voit Commercial.
1 office space 5,060 square feet.
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444 C St, San Diego, CA 92101
444 C St is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by Venture Pacific Commercial Services.
1 office space 850 square feet.
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1010 Turquoise St, San Diego, CA 92109
1010 Turquoise St is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by Voit Commercial.
Office space for lease
2 office spaces from 1,147 to 10,738 square feet.
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