San Diego, CA Commercial Real Estate - Office, Warehouses, and Retail Space

Office spaces in San Diego are seeing increasing demand from technology and life sciences firms, particularly in hubs like UTC, Sorrento Valley, and Downtown. The industrial market remains strong due to e-commerce growth and the region's strategic logistics advantages. Retail spaces are rebounding, with a focus on experiential and mixed-use developments catering to the city's vibrant population and tourism industry. San Diego's business-friendly climate, highly educated workforce, and strong research institutions, including UC San Diego, attract companies seeking innovation and collaboration. Additionally, the city's quality of life—boasting year-round mild weather, cultural amenities, and outdoor activities—further draws talent and businesses to the area.

Rofo researches and displays commercial real estate listings from top brokerage firms and landlords in San Diego, CA making it easier to find available commercial space and compare current asking rental rates. In San Diego, CA there are currently 1,454 office spaces for lease, 289 warehouse spaces for rent, 223 retail spaces, and 230 shared office spaces (also known as co-working spaces and executive suites) with 167 real estate professionals to help you find the right space for you. Sizes range from 200 square feet up to 10,997,805 square feet. Filter your search below and get free advice from recommended brokers in San Diego, CA.

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Showing 1 - 20 of 210 buildings with 200 total listings

770 First Avenue, San Diego, CA 92101

770 First Avenue is an office property for lease in San Diego, CA. The property currently has 5 office spaces for lease and is marketed by Regus.

Virtual office in CA, San Diego - 770 First Avenue

5 office spaces from 54 to 328 square feet.

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9920 Pacific Heights Blvd, San Diego, CA 92121

9920 Pacific Heights Blvd is an office property for lease in San Diego, CA. The property currently has 10 office spaces for lease and is marketed by Regus.

Prominent glass building Build a modern home for your business in San DiegoÕs major tech hub. Spread across the first floor of a dazzling, glass-panelled...

10 office spaces from 11 to 14,076 square feet.

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845 15th St, San Diego, CA 92101

845 15th St is an office property for lease in San Diego, CA. The property currently has 8 office spaces for lease and is marketed by Regus.

ITS TIME TO CREATE AT SPACES MAKERS QUARTER IN SAN DIEGO. East Village, San Diego, has become a nexus of redevelopment in SoCal, with the new-build...

8 office spaces from 11 to 323 square feet.

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501 W Broadway, San Diego, CA 92101

501 W Broadway is an office property for lease in San Diego, CA. The property currently has 12 office spaces for lease and is marketed by , ABCNRegus and Search Office Space.

With its distinctive arched entry, granite exterior and marble finishes, this is one of Downtown’s finest jewels. Panoramic views and an...

12 office spaces from 11 to 13,478 square feet.

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4445 Eastgate Mall, Suite 200, San Diego, CA 92121

4445 Eastgate Mall, Suite 200 is an office property for lease in San Diego, CA. The property currently has 10 office spaces for lease and is marketed by Regus.

Dynamic campus community You!lmost guaranteed to learn something while working from University City. Minutes from the San Diego campus, Sunroad...

10 office spaces from 11 to 484 square feet.

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350 10th Avenue, San Diego, CA 92101

350 10th Avenue is an office property for lease in San Diego, CA. The property currently has 10 office spaces for lease and is marketed by Regus.

this 306,750 SF Class A office tower provides 15 floors with amazing views to all levels of the stadium, downtown and the bay.

10 office spaces from 11 to 484 square feet.

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3111 Camino del Rio N, San Diego, CA 92108

3111 Camino del Rio N is an office property for lease in San Diego, CA. The property currently has 10 office spaces for lease and is marketed by Regus.

Centerside consists of two striking towers in the heart of Mission Valley. The 13 and 16-story towers include 490,000 SF of office space with...

10 office spaces from 11 to 1,992 square feet.

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2305 Historic Decatur Rd, San Diego, CA 92106

2305 Historic Decatur Rd is an office property for lease in San Diego, CA. The property currently has 10 office spaces for lease and is marketed by Regus.

105,061 SF Class A Office Building

10 office spaces from 11 to 484 square feet.

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1420 Kettner Blvd, San Diego, CA 92101

1420 Kettner Blvd is an office property for lease in San Diego, CA. The property currently has 9 office spaces for lease and is marketed by Regus.

Engage with a community of like-minded professionals at Kettner Commons Located on the south side of the chic and attractive Little Italy neighborhood,...

9 office spaces from 11 to 484 square feet.

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12707 & 12777 High Bluff Drive, San Diego, CA 92130

12707 & 12777 High Bluff Drive is an office property for lease in San Diego, CA. The property currently has 11 office spaces for lease and is marketed by Regus.

Major Renovations coming soon including new hardscape, enhanced exterior facades, new lobby, corridors and restrooms, new signage, enhanced courtyard...

11 office spaces

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10620 Treena St, San Diego, CA 92131

10620 Treena St is an office property for lease in San Diego, CA. The property currently has 10 office spaces for lease and is marketed by Regus.

Centrally located in Scripps Ranch, fronting Interstate 8. Equal distance from State Route 52 and 56. Adjacent communities of Mira Mesa, Carmel...

10 office spaces from 11 to 800 square feet.

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2174 Logan, San Diego, CA 92113

2174 Logan is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

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3386 University Ave, San Diego, CA 92104

3386 University Ave is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

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2751 Imperial Ave, San Diego, CA 92102

2751 Imperial Ave is an office property for lease in San Diego, CA. The property currently has 2 office spaces for lease and is marketed by CBC Corporate.

2 office spaces

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2795 B St, San Diego, CA 92102

2795 B St is an office property for lease in San Diego, CA. The property currently has 4 office spaces for lease and is marketed by CBC Corporate.

4 office spaces

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837 S 47th St, San Diego, CA 92113

837 S 47th St is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

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1767 Palm Avenue, San Diego, CA 92154

1767 Palm Avenue is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

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2607 1st, San Diego, CA 92103

2607 1st is an office property for lease in San Diego, CA. The property currently has 3 office spaces for lease and is marketed by CBC Corporate.

3 office spaces

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5933-43 El Cajon Boulevard, San Diego, CA 92115

5933-43 El Cajon Boulevard is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

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6575 El Cajon Bl, San Diego, CA 92115

6575 El Cajon Bl is an office property for lease in San Diego, CA. The property currently has 1 office space for lease and is marketed by CBC Corporate.

1 office space

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- Brandon Heath, San Diego agent and Rofo Pro